Aloe emodin

Aloe emodin
Systematic (IUPAC) name
1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
Clinical data
Pregnancy cat.  ?
Legal status  ?
Routes Oral
Identifiers
CAS number 481-72-1 Y
ATC code None
PubChem CID 10207
ChemSpider 9792 Y
KEGG C10294 Y
ChEMBL CHEMBL40275 Y
Chemical data
Formula C15H10O5 
Mol. mass 270.24
SMILES eMolecules & PubChem
Physical data
Melt. point 223–224 °C (433–435 °F) Sublimes in CO2 stream
 Y(what is this?)  (verify)

Aloe emodin is a carcinogenic[1][2] anthraquinone present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action.[3]

References

  1. ^ Badgwell, DB; Walker, CM; Baker, WT; Strickland, FM (2004). "Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors". Molecular carcinogenesis 39 (3): 127–38. doi:10.1002/mc.10170. PMID 14991742. 
  2. ^ National Toxicology, Program (2010). "Photocarcinogenesis study of aloe vera CAS NO. 481-72-1(Aloe-emodin) in SKH-1 mice (simulated solar light and topical application study)". National Toxicology Program technical report series (553): 7–33, 35–97, 99–103 passim. PMID 21031007. 
  3. ^ The Merck Index, 12th Edition. 313.

See also